Serogrouping Shigella in the clinical laboratory is based on which antigen?

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Prepare for the Clinical Laboratory Science Bacteriology Test. Engage with multiple choice questions and flashcards with helpful hints and explanations. Ace your exam confidently!

Multiple Choice

Serogrouping Shigella in the clinical laboratory is based on which antigen?

Explanation:
Shigella serogrouping is determined by the somatic (O) antigen of the lipopolysaccharide. Shigella species are nonmotile, so they do not have flagellar H antigens, which means H cannot be used for grouping. The O antigen patterns, identified with specific antisera in the Kauffmann-White scheme, differentiate the main Shigella serogroups. Capsule (K) antigens aren’t used for Shigella serogrouping, and bacteriocins don’t define serogroups. So, the key concept is that the O antigen is the basis for serogrouping.

Shigella serogrouping is determined by the somatic (O) antigen of the lipopolysaccharide. Shigella species are nonmotile, so they do not have flagellar H antigens, which means H cannot be used for grouping. The O antigen patterns, identified with specific antisera in the Kauffmann-White scheme, differentiate the main Shigella serogroups. Capsule (K) antigens aren’t used for Shigella serogrouping, and bacteriocins don’t define serogroups. So, the key concept is that the O antigen is the basis for serogrouping.

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